Capecitabine

Colorectal cancer is cancer that develops in the large intestine. Common symptoms include changes in bowel patterns, abdominal discomfort, fatigue, weight loss. Colorectal cancer is more common in men than women. Overall, the frequency of colorectal cancer is higher in industrial and urban areas. Most patients with colorectal cancer are over 60 years old at the time of diagnosis.

Capecitabine trademarks: Binecap, Taceral, Xeloda

Treatment is generally a combination of therapies that include acting on the cancer locally, such as surgery or radiotherapy or acting on cancer cells systemically (throughout the body) such as chemotherapy and biologically targeted therapies. The scope of treatment will depend on the stage of the cancer, and on the characteristics of the tumor and its characteristics. risk to the patient.

Surgery aims to remove the primary tumor / main. In patients with advanced disease, surgery is also performed to remove metastatic lesions.

In patients presenting with high-risk disease, adjuvant chemotherapy is recommended. Chemotherapy is given in addition to the main treatment, namely initial surgery, to prevent the tumor from reappearing. Fluoropyridine is one of a group of substances used to treat cancer. An example of a fluoropyrimidine is capesitabin. Capesitabin is a type of antimetabolite.

Biological target therapy should be considered in selected patients. After the initial period of combination chemotherapy, maintenance/maintenance treatment may improve outcomes compared to treatment breaks, and resumption of combination chemotherapy is recommended if worsening occurs. The principle behind maintenance treatment is to continue to use drugs that have been well tolerated. May be considered consisting of 5-FU or capecitabine, in combination with bevacizumab.

Radiotherapy or radiotherapy combined with chemotherapy (chemoradiotherapy), is performed before surgery for certain stages of rectal cancer. Surgery is usually performed 6-8 weeks after chemoradiotherapy is completed. In rectal cancer, radiotherapy and chemoradiotherapy are recommended preoperatively if possible. In experienced healthcare centers, brachytherapy or special contact techniques may be used as an alternative to local surgery (with or without adjuvant chemoradiotherapy) for certain types of rectal cancer.

All available treatments have their own benefits, risks and contraindications. Patients are recommended to ask their doctor about the expected benefits and risks of each treatment so that patients are aware of the consequences of treatment.

Abouts:

- Severe and Late Acute Liver Injury Induced by Capecitabine.
- Identification of Biomarkers Predicting The Chemotherapeutic Outcomes ff Capecitabine and Oxaliplatin in Patients with Gastric Cancer.
- Medline Plus. Capecitabine.
- Capecitabine.
- Capecitabine (Xeloda).
- Capecitabine (Oral Route).
- Capecitabine (Rx).
- Capecitabine Tablets.